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Non-coding mutation

Q.

The following is a eukaryotic DNA sequence. The coding sequence of the gene is in bold and italicized, and the promoter is underlined.

DNA 5’   T G*A A G G A A T T A T A A T A C G A C C ... A T G A T G T A C G C A T A A A C G T   3’

A mutation occurs in which a base (T) is inserted into the DNA sequence after the G, at the position marked with an asterisk, before transcription begins. How will this alteration influence the mRNA produced?

Audiences:

Undergraduate

Topics:

Biology,  V & C Core Concept 3: Info Flow, Exchange and Storage,  Genetics Concept Assessment

Associated Publications

Characterizing students ideas about the effects of a mutation in a noncoding region of DNA

Scott Sieke, Betsy McIntosh, Matthew Steele, Jennifer Knight, 2019

Question Instructions

We recommend that you administer these questions as homework and preface the question with these instructions for students:

"For the following question, please respond to the best of your knowledge and using only the information in the question and what you know. Please do not refer to any outside sources (textbooks, notes, internet, etc.). Any reasonable attempt to answer the question will be awarded full credit."

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